Next Science Limited advises, in accordance with ASX Listing Rule 3.14, of the relocation of its head office to the offices of the Company's lawyers, HWL Ebsworth, Level 14, Australia Square, 264-278 George Street, Sydney. The decision to relocate the Company's head office aligns with the Company's previously announced strategic decision to move the Chief Executive Officer and Chief Financial Officer roles to the Company's office in Jacksonville, Florida, USA. The Jacksonville office is the base for the Company's commercial activities, research and development (including its internal laboratory), and regulatory functions, as well as the supply chain and commercial operation of the DME Business.

The office houses 50 staff out of a total US headcount of over 100 staff. Effective 6 July 2023, the Company's registered office address and principal place of business in Australia is: HWL Ebsworth Level 14, Australia Square 264-278 George Street Sydney NSW 2000.