Aytu BioPharma, Inc. and Medomie Pharma Ltd. announced the signing of an exclusive collaboration, distribution and supply agreement for Aytu's Adzenys XR-ODT and Cotempla XR-ODT product lines. Medomie will seek local regulatory approvals and marketing authorizations for both Adzenys and Cotempla. This agreement represents Aytu's first international commercial agreement for Adzenys and Cotempla.