On November 16, 2018, Harry D’Andrea,  a director of OpGen, Inc, resigned from the Board of Directors and from all committees of the Board of Directors on which he served.  Mr. D’Andrea served as a member of and Chair of the Audit Committee.  There was no disagreement between Mr. D’Andrea and the Company leading to his decision to resign. Also on November 16, 2018, the Board appointed Tina Nova to serve as a member of the Audit Committee of the Board of Directors.  The Board assessed her qualifications for serving in such capacity, including her roles as the chief executive officer of a number of companies and her prior service on the Audit Committee of other publicly traded companies, and re-assessed her status as an independent member of the Board of Directors. Dr. Nova was confirmed as an independent member of the Board of Directors with the necessary financial statement expertise to serve as a member of the Audit Committee.