Glenmark Pharmaceuticals Limited (Glenmark Pharma), has launched in India the first triple-drug fixed-dose combination (FDC) of the widely-used Teneligliptin with Dapagliflozin and Metformin. This FDC has been launched under the brand name Zita® DM, and it contains the DPP4 inhibitor, Teneligliptin (20mg), the SGLT2 inhibitor, Dapagliflozin, (10mg), and Metformin SR (500mg/1000mg) in a fixed dose. It must be taken once daily, under prescription, to improve glycemic control in patients with Type 2 diabetes.

Glenmark's Zita portfolio of medicines have been benefiting around 1.75 million Type 2 diabetic patients annually, in India. With the launch of Zita DM, Zita the most comprehensive gliptin range now holds promise of helping Type 2 diabetic patients at every stage of their treatment. According to IQVIATM sales data for the 12month period ending August 2023 (MAT August 2023), the market for oral antidiabetic drugs in India is estimated to be INR 12,522 crores, with an annual growth of 6.5% against the corresponding period last year (MAT August 2022).

As per the ICMR-INDIAB study conducted between 17th October 2008 and 17th December 2020, the overall weighted prevalence of diabetes was 11.4%. Glenmark's Leadership in the Diabetes Segment: Glenmark has a strong legacy of bringing in new, effective, and affordable treatment options for diabetic patients, especially with uncontrolled Type 2 diabetes. In 2015, Glenmark was the first to launch the DPP4 inhibitor, Teneligliptin (Zita Plus and Ziten), followed by a FDC of Teneligliptin + Metformin (Zita-Met Plus and Ziten-M).

Glenmark later introduced Remogliflozin (Remo and RemozenTM), a novel SGLT-2 inhibitor in 2019; and subsequently, its combinations (Remo-V, RemozenTM-V, Remo MV, and RemozenTM MV). Glenmark followed that up with the launch of Sitagliptin (Sitazit) and its FDCs in 2022. Then came Lobeglitazone (LOBG®) and additional FDCs of Teneligliptin, including its combinations with Pioglitazone (Zita PioTM), Pioglitazone + Metformin (Zita-PioMet), and Dapagliflozin (Zita-DTM).