Shanghai - Antengene Corporation Limited ('Antengene' SEHK: 6996.HK), today introduced a round of voluntary price cut for XPOVIO (selinexor) in an effort to improve the drug's accessibility and affordability for patients paying for their treatment out-of-pocket, thus allowing more patients with multiple myeloma (MM) in China to benefit from the drug.
This voluntary price cut will lower the price of XPOVIO in 20mg 12 tablets/box from RMB22,435 to RMB14,135, and the price of XPOVIO in 20mg 16 tablets/box from RMB29,600 to RMB18,649.67, by a ratio of approximately 37%. To allow patients to benefit from this price cut as soon as possible, Antengene will update the list-price for XPOVIO across the Mainland of China and advise direct-to-patient (DTP) and retail pharmacies in the country to make adjustments to the drug's retail prices.
XPOVIO is world's first approved orally-available selective inhibitor of the nuclear export protein (XPO1) that utilizes a novel mechanism of action. Since approved in the Mainland of China in December 2021, XPOVIO was commercially launched in the country in May 13, 2022, for the treatment of patients relapsed/refractory MM (R/R MM).
Dr. Jay Mei, Antengene's Founder, Chairman and CEO, said, 'MM is a malignancy caused by the dysregulated proliferation of plasma cells. In recent years, we have seen notable progress in the treatment of R/R MM. However, R/R MM remains largely incurable disease that is prone to relapses, therefore continues to represent a huge unmet medical need. XPOVIO, an oral drug utilizing a novel mechanism of action, offers significant efficacy and clinically meaningful survival benefits to patients. While introducing this round of voluntary price cut with the aim of improving the drug's affordability for out-of-pocket patients, we are in active preparation to facilitate a potential inclusion of XPOVIO into China's National Reimbursement Drug List (NRDL), which once achieved, will further improve the accessibility of the drug to patients in the Mainland of China. Meanwhile, we will continue to explore XPOVIO's potential for indication expansions in order to bring an effective, accessible and affordable novel treatment option to more patients in the APAC region and across the globe.'
About Antengene
Antengene Corporation Limited ('Antengene', SEHK: 6996.HK) is a leading commercial-stage R&D-driven global biopharmaceutical company focused on the discovery, development, manufacturing and commercialization of innovative first-in-class/best-in-class therapeutics for the treatment of hematologic malignancies and solid tumors, in realizing its vision of 'Treating Patients Beyond Borders'.
Since 2017, Antengene has built a pipeline of 9 oncology assets at various stages going from clinical to commercial, including 6 with global rights, and 3 with rights for the APAC region. To date, Antengene has obtained 29 investigational new drug (IND) approvals in the U.S. and Asia, and submitted 10 new drug applications (NDAs) in multiple Asia Pacific markets, with the NDA for XPOVIO (selinexor) already approved in Mainland of China, Taiwan China, Hong Kong China, South Korea, Singapore and Australia.
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