ALX Oncology Holdings Inc.

Equities

ALXO

US00166B1052

Biotechnology & Medical Research

Market Closed - Nasdaq Other stock markets 04:00:00 2024-04-26 pm EDT			5-day change	1st Jan Change
16.86 ^USD	-0.06%		+8.08%	+13.23%

Apr. 18	Alx Oncology Holdings Insider Sold Shares Worth $710,195, According to a Recent SEC Filing	MT
Apr. 10	ALX Oncology Reports Positive Data From Ongoing Phase 1/2 Trial of Evorpacept	MT

ALX Oncology, Eli Lilly to Evaluate Gastric Cancer Treatment

June 10, 2021 at 05:35 am EDT

By Chris Wack

ALX Oncology Holdings Inc. said it has entered into a clinical trial collaboration and supply agreement with Eli Lilly & Co. to evaluate the combination of ALX148, a next-generation CD47 blocker, and Cyramza ramucirumab, Lilly's anti-VEGFR2 antibody, for the treatment of patients with HER2-positive gastric cancer or gastroesophageal junction cancer.

Under the terms of the agreement, ALX Oncology will conduct a randomized Phase 2/3 study to evaluate the efficacy of ALX148 in combination with ramucirumab, trastuzumab, and paclitaxel for the treatment of patients whose tumors have progressed following treatment with HER2-targeted therapy and chemotherapy. Lilly will supply ramucirumab for this trial.

Financial details of the collaboration agreement are undisclosed.

ALX Oncology owns worldwide commercial rights to ALX148.

Write to Chris Wack at chris.wack@wsj.com

(END) Dow Jones Newswires

06-10-21 0735ET

Latest news about ALX Oncology Holdings Inc.

Alx Oncology Holdings Insider Sold Shares Worth $710,195, According to a Recent SEC Filing	Apr. 18	MT
ALX Oncology Reports Positive Data From Ongoing Phase 1/2 Trial of Evorpacept	Apr. 10	MT
ALX Oncology Holdings Inc. Reports Encouraging Clinical Data of Evorpacept in Combination with Standard-of-Care in an Ongoing Phase 1/2 Clinical Trial in Patients with Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (?R/R B-NHL?)	Apr. 09	CI
UBS Adjusts ALX Oncology Price Target to $25 From $27, Maintains Buy Rating	Mar. 13	MT
H.C. Wainwright Adjusts Price Target on ALX Oncology to $20 From $17.50, Keeps Buy Rating	Mar. 11	MT
North American Morning Briefing : Stock Futures -2-	Mar. 11	DJ
Piper Sandler Adjusts Price Target on ALX Oncology Holdings to $21 From $11, Maintains Overweight Rating	Mar. 08	MT
Stifel Downgrades ALX Oncology Holdings to Hold From Buy, Adjusts Price Target to $14 From $10	Mar. 08	MT
ALX Oncology Holdings Inc. Reports Earnings Results for the Full Year Ended December 31, 2023	Mar. 07	CI
ALX Oncology Holdings Inc. Reports Earnings Results for the Fourth Quarter Ended December 31, 2023	Mar. 07	CI
Transcript : ALX Oncology Holdings Inc. Presents at J.P. Morgan 42nd Annual Healthcare Conference 2024, Jan-08-2024 through Jan-11-2024	Jan. 08
ALX Oncology Holdings Inc. and ALX Oncology Inc. Enter into the Third Amendment to Loan and Security Agreement	Dec. 26	CI
North American Morning Briefing : Investors Await -2-	Dec. 11	DJ
Top Midday Gainers	Dec. 08	MT
Jefferies Upgrades ALX Oncology to Buy From Hold, Adjusts Price Target to $18 From $8	Dec. 08	MT
Stifel Trims ALX Oncology Holdings' Price Target to $10 From $11, Maintains Buy Rating	Nov. 14	MT
Sector Update: Health Care Stocks Advance Premarket Tuesday	Nov. 14	MT
ALX Oncology Reports Q3 Results With 'Sufficient' Funds to Finance Operations Into Early 2026	Nov. 13	MT
ALX Oncology Q3 Net Loss Widens; Shares Ease After Hours	Nov. 13	MT
ALX Oncology Holdings Inc. Reports Earnings Results for the Third Quarter and Nine Months Ended September 30, 2023	Nov. 13	CI
Transcript : ALX Oncology Holdings Inc. Presents at UBS Biopharma Conference 2023, Nov-08-2023 01:30 PM	Nov. 08
Piper Sandler Raises Price Target on ALX Oncology to $11 From $8, Maintains Overweight Rating	23-10-11	MT
ALX Oncology Closes $63.2 Million Common Stock, Warrants Offering to Fund Clinical Development of Evorpacept	23-10-10	MT
ALX Oncology Prices Underwritten Offering of Common Stock, Warrants for Expected Gross Proceeds of $55 Million	23-10-05	MT
ALX Oncology Commences Common Stock, Warrants Offering to Fund Development of Evorpacept	23-10-04	MT

Chart ALX Oncology Holdings Inc.

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Company Profile

ALX Oncology Holdings Inc. is a clinical-stage immuno-oncology company focused on helping patients fight cancer by developing therapies that block the CD47 immune checkpoint inhibitor and bridge the innate and adaptive immune system. Its product candidate, evorpacept, is a CD47 blocking therapeutic that combines a high-affinity CD47 binding domain with an inactivated, proprietary Fc domain. It is engaged in focusing on combining evorpacept with anti-cancer antibodies, ADCs, and PD-1/PD-L1 immune checkpoint inhibitors. Cancer cells leverage CD47, a cell surface protein, as a donât eat me signal to evade macrophage phagocytosis or as a don't activate T-cells signal that prevents activation of T-cells by dendritic cells. It focuses on combining evorpacept with anti-cancer antibodies, ADCs, and PD-1/PD-L1 immune checkpoint inhibitors. It also has a preclinical program focused on developing ALTA-002, a SIRPa TRAAC that offers ways to engage the innate and adaptive immune response to cancer.

Sector

Biotechnology & Medical Research

Calendar

2024-05-07 - Q1 2024 Earnings Release (Projected)

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Analysts' Consensus

Sell

Buy

Mean consensus

BUY

Number of Analysts

Last Close Price

16.87 USD

Average target price

20.17 USD

Spread / Average Target

+19.54%

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