International stocks trading in New York closed mostly lower on Wednesday.

The S&P/BNY Mellon index of American depositary receipts declined 0.7% to 164.87. The Asian index fell 1.5% to 222.50. The Latin American index fell 1.7% to 173.62. And the emerging-markets index fell 1.5% to 366.49.

Meanwhile, the European index improved 0.03% to 146.81.

Baidu Inc. was among those whose ADRs traded actively.

The U.S. government has agreed to buy more doses of an antibody drug for the early treatment of Covid-19 developed by GlaxoSmithKline PLC and Vir Biotechnology Inc., bringing its total order to nearly $1 billion for a treatment found to reduce the risk of hospitalization. ADRs closed 0.2% higher at $42.55.

Baidu Inc. posted a net loss of 16.56 billion yuan ($2.59 billion) for the third quarter due to a significant non-cash loss in long-term investments. The quarterly net loss by the Chinese search-engine giant on Wednesday sharply missed the consensus estimate, according to FactSet. ADRs fell 5.5% to $161.82.


 
 -- WSJ Staff 
 
 

(END) Dow Jones Newswires

11-17-21 1933ET