Charles Sigal
Director/Board Member at VIR BIOTECHNOLOGY, INC.
Net worth: 656 989 $ as of 2024-03-30
Profile
Charles Elliott Sigal is currently serving as a Director at Medarex, Inc. He is also an Independent Director at Alnylam Pharmaceuticals, Inc., Vir Biotechnology, Inc., Affinia Therapeutics, Inc., and Tessera Therapeutics, Inc. Additionally, he holds positions as a Member of the Drug Discovery & Development Forum at the National Academy of Medicine (United States) and a Member of the President Council at The J.
David Gladstone Institutes.
Dr. Sigal is a Trustee at University Medical Center and manages Segal Family Investments LLC.
In his former roles, Dr. Sigal served as the Chief Executive Officer and Vice President of R&D at Mercator Genetics, Inc. He was also the Director, Chief Scientific Officer, and Executive VP at Bristol Myers Squibb Co. from 2011 to 2013.
Additionally, he held the position of Director at Mead Johnson Nutrition Co. from 2012 to 2017.
Dr. Sigal served as an Independent Director at Spark Therapeutics, Inc. from 2014 to 2019 and as an Independent Non-Executive Director at Surface Oncology, Inc. from 2018 to 2023.
He also served as an Independent Non-Executive Director at Adaptimmune Therapeutics Plc from 2015 to 2023.
Furthermore, Dr. Sigal was a Non-Executive Director at Adaptimmune Ltd.Dr. Sigal obtained his doctorate degree from The University of Chicago in 1981.
He pursued his graduate studies at Purdue University and completed his undergraduate and second doctorate degrees there in 1973 and 1977, respectively.
Known holdings in public companies
| Company | Date | Number of shares | Valuation | Valuation date |
|---|---|---|---|---|
| 2024-01-30 | 2,000 ( 0.00% ) | 298 900 $ | 2024-03-30 | |
VIR BIOTECHNOLOGY, INC.
0.02% | 2023-05-21 | 25,806 ( 0.02% ) | 261 415 $ | 2024-03-30 |
| 2023-07-02 | 367,038 ( 0.06% ) | 96 674 $ | 2024-03-30 |
Charles Sigal active positions
| Companies | Position | Start |
|---|---|---|
| VIR BIOTECHNOLOGY, INC. | Director/Board Member | 2020-07-01 |
| ALNYLAM PHARMACEUTICALS, INC. | Director/Board Member | 2022-08-21 |
| Melanoma Research Alliance | Director/Board Member | 2013-10-31 |
Tessera Therapeutics, Inc.
 Tessera Therapeutics, Inc. BiotechnologyHealth Technology Tessera Therapeutics, Inc. engages in science company. It offers scientists and doctors the ability to write and rewrite small and large therapeutic messages into the genome, thereby curing diseases at their source. The company is headquartered in Cambridge, MA. | Director/Board Member | 2021-06-14 |
Affinia Therapeutics, Inc.
 Affinia Therapeutics, Inc. BiotechnologyHealth Technology Affinia Therapeutics, Inc. is a preclinical stage company, which engages in the research and development of gene therapy. It offers Affinia Rationally-designed Therapies (ART) platform, which develops novel therapies, focusing on the key components of a gene therapy: capsids, which are the outer shells of a virus used to package the genetic code to treat a disease; promoters, which control how the cells read the genetic code that is delivered; and manufacturing approaches, which determine the quality and cost of potential medicines. The company was founded by Luk Vandenberghe, Botond Roska, and Aaron Tward in 2019 and is headquartered in Waltham, MA. | Director/Board Member | 2020-06-07 |
| Segal Family Investments LLC | Corporate Officer/Principal | - |
National Academy of Medicine (United States)
 National Academy of Medicine (United States) Miscellaneous Commercial ServicesCommercial Services The National Academy of Medicine (United States) is based in Washington and is focused on improving the health and well-being of individuals through various initiatives. These initiatives include the clinician well-being collaborative, which aims to accelerate the implementation of a national plan for health workforce well-being, and the development of a code of conduct for the use of artificial intelligence in health care. The organization also provides resources to support meaningful community engagement in health and health care programs and policies. Recently, the National Academy of Medicine announced the appointment of Mandy Cohen, a member of the organization, as the director of the Centers for Disease Control and Prevention. Additionally, the organization has released a publication celebrating 50 years of progress in biomedical science, health, and health care. | Corporate Officer/Principal | - |
The J. David Gladstone Institutes
 The J. David Gladstone Institutes Miscellaneous Commercial ServicesCommercial Services The J. David Gladstone Institutes operates as an independent state-of-the-art biomedical research institution. The company was founded in 1979 and is headquartered in San Francisco, CA. | Corporate Officer/Principal | - |
Medarex, Inc.
 Medarex, Inc. Miscellaneous Commercial ServicesCommercial Services Medarex, Inc. provides commercial physical and biological research services. The company's UltiMAb, a human antibody development system creates and develops antibodies products for cancer, rheumatoid arthritis, inflammatory, autoimmune, and infectious diseases. The company was founded in 1987 and is headquartered in Princeton, New Jersey. | Director/Board Member | - |
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Former positions of Charles Sigal
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Training of Charles Sigal
| The University of Chicago | Doctorate Degree |
| Purdue University | Graduate Degree |
Experiences
Positions held
Connections
1st degree connections
1st degree companies
Male
Female
Members of the board
Executives
Linked companies
| Listed companies | 4 |
|---|---|
| BRISTOL-MYERS SQUIBB COMPANY | Health Technology |
| ALNYLAM PHARMACEUTICALS, INC. | Health Technology |
| VIR BIOTECHNOLOGY, INC. | Health Technology |
| ADAPTIMMUNE THERAPEUTICS PLC | Health Technology |
| Private companies | 14 |
|---|---|
Medarex, Inc.
Medarex, Inc. Miscellaneous Commercial ServicesCommercial Services Medarex, Inc. provides commercial physical and biological research services. The company's UltiMAb, a human antibody development system creates and develops antibodies products for cancer, rheumatoid arthritis, inflammatory, autoimmune, and infectious diseases. The company was founded in 1987 and is headquartered in Princeton, New Jersey. | Commercial Services |
Mead Johnson Nutrition Co.
 Mead Johnson Nutrition Co. Food: Meat/Fish/DairyConsumer Non-Durables Mead Johnson Nutrition Co. produces infant and children's nutrition products. The firm offers Enfamil brand. The firm's product portfolio includes: children nutrition, nutrition for infants, for the dietary management of protein allergies, nutrition for preterm, low birth weight babies, for expecting or breastfeeding moms. The company was founded by Edward Mead Johnson, Sr. in 1905 and is headquartered in Chicago, IL. | Consumer Non-Durables |
Mercator Genetics, Inc.
 Mercator Genetics, Inc. Miscellaneous Commercial ServicesCommercial Services Part of Progenitor, Inc., Mercator Genetics, Inc. develops gene therapy programs for asthma, schizophrenia, and cancer. The private company is based in Menlo Park, CA. Mercator Genetics was acquired by Progenitor, Inc. on February 18, 1997 for $22 million. | Commercial Services |
Penn Medicine Princeton Health
 Penn Medicine Princeton Health Hospital/Nursing ManagementHealth Services Penn Medicine Princeton Health provides health care services. It serves the lifelong needs of central New Jersey residents, including acute care hospital services through University Medical Center of Princeton, behavioral healthcare through Princeton House Behavioral Health, rehabilitation, home care, hospice care, ambulatory surgery, a medical practice, and fitness and wellness services. The company was founded in 1978 and is headquartered in Plainsboro, NJ. | Health Services |
National Academy of Medicine (United States)
National Academy of Medicine (United States) Miscellaneous Commercial ServicesCommercial Services The National Academy of Medicine (United States) is based in Washington and is focused on improving the health and well-being of individuals through various initiatives. These initiatives include the clinician well-being collaborative, which aims to accelerate the implementation of a national plan for health workforce well-being, and the development of a code of conduct for the use of artificial intelligence in health care. The organization also provides resources to support meaningful community engagement in health and health care programs and policies. Recently, the National Academy of Medicine announced the appointment of Mandy Cohen, a member of the organization, as the director of the Centers for Disease Control and Prevention. Additionally, the organization has released a publication celebrating 50 years of progress in biomedical science, health, and health care. | Commercial Services |
The J. David Gladstone Institutes
The J. David Gladstone Institutes Miscellaneous Commercial ServicesCommercial Services The J. David Gladstone Institutes operates as an independent state-of-the-art biomedical research institution. The company was founded in 1979 and is headquartered in San Francisco, CA. | Commercial Services |
University Medical Center
 University Medical Center Medical/Nursing ServicesHealth Services University Medical Center operates as a medical group. The non-profit company is based in Jacksonville, FL. The company was founded by Kathy Stout-Labauve. | Health Services |
Adaptimmune Ltd.
 Adaptimmune Ltd. Medical/Nursing ServicesHealth Services Adaptimmune Ltd. develops T cell therapies to treat cancer, human immunodeficiency virus, and infectious diseases. It utilizes the T cell to target and destroy cancerous and infected cells by using affinity T cell receptor proteins as a means of strengthening patient T cell responses. The company was founded by Bent K. Jakobsen, James Julian Noble and Helena Katrina Tayton-Martin in 2008 and is headquartered in Oxford, the United Kingdom. | Health Services |
Spark Therapeutics, Inc.
 Spark Therapeutics, Inc. BiotechnologyHealth Technology Spark Therapeutics, Inc. engages in the research, development, and commercialization of gene therapies. Its product portfolio intends to treat inherited retinal sickness, liver-mediated, and neurodegenerative diseases. The company was founded by Jean Bennett, Beverly Davidson, Katherine A. High, Jeffrey D. Marrazzo, J. Fraser Wright, and Jennifer Wellman on March 13, 2013 and is headquartered in Philadelphia, PA. | Health Technology |
| Melanoma Research Alliance | Miscellaneous |
Surface Oncology, Inc.
 Surface Oncology, Inc. BiotechnologyHealth Technology Surface Oncology, Inc. operates as a clinical-stage immuno-oncology company, which engages in the provision of biological pathways critical to the immunosuppressive tumor microenvironment for the development of next-generation cancer therapies. The firm’s pipeline includes wholly-owned lead programs targeting CD39 (SRF617) and IL-27 (SRF388), as well as a preclinical program focused on depleting tumor regulatory T cells via targeting CCR8 (SRF114). Its pipeline also includes licensed product programs, such as a collaboration with Novartis targeting CD73 (NZV930, Phase 1) and a collaboration with GlaxoSmithKline targeting PVRIG (SRF813, preclinical). The company was founded by David S. Grayzel in 2014 and is headquartered in Cambridge, MA. | Health Technology |
Affinia Therapeutics, Inc.
Affinia Therapeutics, Inc. BiotechnologyHealth Technology Affinia Therapeutics, Inc. is a preclinical stage company, which engages in the research and development of gene therapy. It offers Affinia Rationally-designed Therapies (ART) platform, which develops novel therapies, focusing on the key components of a gene therapy: capsids, which are the outer shells of a virus used to package the genetic code to treat a disease; promoters, which control how the cells read the genetic code that is delivered; and manufacturing approaches, which determine the quality and cost of potential medicines. The company was founded by Luk Vandenberghe, Botond Roska, and Aaron Tward in 2019 and is headquartered in Waltham, MA. | Health Technology |
Tessera Therapeutics, Inc.
Tessera Therapeutics, Inc. BiotechnologyHealth Technology Tessera Therapeutics, Inc. engages in science company. It offers scientists and doctors the ability to write and rewrite small and large therapeutic messages into the genome, thereby curing diseases at their source. The company is headquartered in Cambridge, MA. | Health Technology |
| Segal Family Investments LLC |
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