Oncopeptides AB announced the final topline results from the pivotal phase 2 HORIZON study evaluating melflufen in relapsed refractory multiple myeloma (RRMM) patients. These results will form the basis for the upcoming NDA for accelerated approval in the US. The application is on track for a submission to the FDA at the end of second quarter of 2020. The final HORIZON results represent an Overall Response Rate (ORR) improvement for triple-class refractory RRMM patients compared to the interim data presented at the American Society of Hematology (ASH) meeting in December 2019. The HORIZON results show a good efficacy and safety profile for melflufen in difficult to treat RRMM patients. The final HORIZON data reinforce Oncopeptides' view that melflufen could play an important role in the treatment of patients with RRMM.