Endo International : ENDP Q2 2023 Slides

Q2 2023 Earnings Report

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©2023 Endo International plc or one of its affiliates. All rights reserved

Forward Looking Statements

This presentation contains forward looking statements within the meaning of the Private Securities Litigation Reform Act of 1 995 and Canadian securities legislation, including, but not limited to, statements with respect to financial guidance, expectations or outlook, business development plans, product l aunches, regulatory filings, clinical studies, expansion or enhancement of our portfolio or pipeline, productivity improvements, the adoption of more sustainable practices, and any o ther statements that refer to expected, estimated or anticipated future results or that do not relate solely to historical facts. Statements including words such as "believes," " expects," "anticipates," "intends," "estimates," "plan," "will," "may," "look forward," "guidance," "future projects" or similar expressions are forward looking statements. Because these sta tements reflect our current views, expectations and beliefs concerning future events, these forward looking statements involve risks and uncertainties. Although Endo believes th at these forward looking statements and information are based upon reasonable assumptions and expectations, readers should not place undue reliance on them, or any other forward looking statements or information in this presentation. Actual results may differ materially and adversely from current expectations based on a number of factors, incl uding, among other things, the following: the timing, impact or results of any pending or future litigation (including any appeals or injunctions), investigations, proceedings or claims, including opioid, tax and antitrust related matters; actual or contingent liabilities; settlement discussions or negotiations; Endo's liquidity, financial performance, cash posit ion and operations; Endo's strategy; risks and uncertainties associated with Chapter 11 proceedings; the negative impacts on Endo's businesses as a result of filing for and operating und er Chapter 11 protection; the time, terms and ability to confirm a sale of Endo's businesses under Section 363 of the U.S. Bankruptcy Code; the adequacy of the capital resources o f Endo's businesses and the difficulty in forecasting the liquidity requirements of the operations of Endo's businesses; the unpredictability of Endo's financial results while in Chapter 11 proceedings; Endo's ability to discharge claims in Chapter 11 proceedings; negotiations with the holders of Endo's indebtedness and its trade creditors and other significant creditors; risks and uncertainties with performing under the terms of the restructuring support agreement and any other arrangement with lenders or creditors while in Chapter 1 1 proceedings; Endo's ability to conduct business as usual; Endo's ability to continue to serve customers, suppliers and other business partners at the high level of service and performance they have come to expect from Endo; Endo's ability to continue to pay employees, suppliers and vendors; the ability to control costs during Chapter 11 proceeding s; adverse litigation; the risk that Endo's Chapter 11 Cases may be converted to cases under Chapter 7 of the Bankruptcy Code; Endo's ability to secure operating capital; Endo's ab ility to take advantage of opportunities to acquire

assets with upside potential; Endo's ability to execute on its strategic plan to pursue, evaluate and close an asset sale of Endo's businesses pursuant to Section 363 of the U.S. Bankruptcy Code; the impact of competition and the timing of competitive entrants; and Endo's ability to advance its strategi c priorities, develop its product pipeline and continue to develop the market for branded and unbranded products. Investors should note that many factors, as more fully described in pr ess releases issued by Endo and in documents filed with securities regulators in the United States and Canada including under the caption "Risk Factors" in Endo's Form 10 -K, Form 10-Q and Form 8-K filings, as applicable, with the

Securities and Exchange Commission and with securities regulators in Canada on System for Electronic Document Analysis and Re trieval (SEDAR) and as otherwise enumerated herein or therein, could affect Endo's future financial results and could cause Endo's actual results to differ materially fr om those expressed in any forward looking statements. The forward looking statements in this presentation are qualified by these risk factors. Endo assumes no obligation to publicly u pdate any forward looking statements, whether as a result of new information, future developments or otherwise, except as may be required under applicable securities law.

2	©2023 Endo International plc or one of its affiliates. All rights reserved

Non-GAAP Financial Measures

This presentation may refer to non-GAAP financial measures, including, among others, adjusted diluted net income per share from continuing operations, adjusted EBITDA, adjusted income from continuing operations, adjusted gross margin, adjusted operating expenses, adjusted effective tax rate, adjusted revenue and adjusted weighted average diluted shares that are not prepared in accordance with accounting principles generally accepted in the United States and tha t may be different from non-GAAP financial measures used by other companies. Endo utilizes these financial measures because (i) they are used by Endo, along with financial measures in accordance with GAAP, to evaluate Endo's operating performance; (ii) Endo believes that they will be used by certain investors to measure Endo's operating results; (i ii) the Compensation & Human Capital Committee of

Endo's Board of Directors uses adjusted diluted net income per share from continuing operations and adjusted EBITDA, or measu res derived from such, in assessing the performance and compensation of substantially all of Endo's employees, including executive officers. Endo believes that prese nting these non-GAAP measures provides useful information about Endo's performance across reporting periods on a consistent basis by excluding certain items, which may be favorable or unfavorable, pursuant to certain specified procedures. These non-GAAP measures should be considered supplemental to and not a substitute for financial information prepared in accordance with GAAP. Endo's definition of these non-GAAP measures may differ from similarly titled measures used by others. Investors are encouraged to revi ew Endo's current report on Form 8-K furnished to the SEC on August 8, 2023, including exhibit 99.1 thereto, for Endo's definition of the non -GAAP financial measures in this presentation as well as a reconciliation of these non-

GAAP financial measures to the most directly comparable GAAP measures.

3	©2023 Endo International plc or one of its affiliates. All rights reserved

Presentation Outline

• Strategic Priorities
• Business Performance
• Pipeline Update
• Financial Results

4	©2023 Endo International plc or one of its affiliates. All rights reserved

Endo: A Diversified Specialty Pharmaceutical Company

Our Vision

Helping everyone we serve live their best life.

Our Mission

We develop and deliver life-enhancing products through focused execution.

Our Strategic Priorities

Expand &

Enhance Our

Portfolio

Reinvent How We Work

Be A Force For Good

5	©2023 Endo International plc or one of its affiliates. All rights reserved