Item 8.01             Entry Into a Material Definitive Agreement.



On November 21, 2019, BioSig Technologies, Inc. (the "Company") issued a press release announcing that the Company commenced its first clinical trial for its PURE EP™ System. A copy of the press release is filed as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated by reference herein.




Item 9.01       Financial Statements and Exhibits.



(d) Exhibits



Exhibit Number   Description
99.1               Press Release, dated November 21, 2019

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