The major sell-off in British assets followed finance minister Kwasi Kwarteng's Friday fiscal statement which cut a raft of taxes without detailing how it would be funded.
Kwarteng, Chancellor of the Exchequer, on Sunday declined to comment on the freefall in the pound, saying he was focussed on longer-term growth and not short-term market reaction.
"The chancellor has made clear that he doesn't comment on the movements around the market and that goes the same for the prime minister," the spokesman said.
The spokesman said there were no plans to make any changes to the measures set out, which he described as "a plan for the medium- to long-term, which is about fundamentally changing our approach to the economy with a focus on growth."
Kwarteng has put the onus on the Bank of England to contain any inflationary effects of the massive fiscal expansion, last week telling governor Andrew Bailey he expects the central bank to take the forceful action necessary to contain inflation.
Asked whether the government expected the BoE, rather than ministers, to do the heavy lifting on containing inflation, Truss's spokesman said a package to help households with energy bills could take 5 percentage points off inflation.
"It is right that we consider how best to control inflation, and of course, that's something the government is mindful of," he said, adding any future tax cuts - hinted at by Kwarteng on Sunday - would be for the finance minister to set out.
(Reporting by Alistair Smout, Writing by Kylie MacLellan)
