Item 8.01 Other Events.

Exhibits are filed herewith in connection with the issuance by American Express Company (the "Company"), on May 26, 2022, of $750,000,000 aggregate principal amount of 4.989% Fixed-to-Floating Rate Subordinated Notes due May 26, 2033 (the "Subordinated Notes") pursuant to a Prospectus Supplement dated May 18, 2022 to the Prospectus dated February 12, 2021, filed as part of the Company's Registration Statement on Form S-3 (No. 333-253057). The Subordinated Notes were issued under the Subordinated Indenture, dated as of August 1, 2007, between the Company and The Bank of New York Mellon (formerly known as The Bank of New York), as trustee (the "Trustee"), as supplemented by a supplemental indenture (the "Supplemental Indenture"), dated as of May 26, 2022 between the Company and the Trustee.

The preceding is a summary of the terms of the Supplemental Indenture and the Subordinated Notes, and is qualified in its entirety by reference to the Supplemental Indenture attached as Exhibit 4.1 and the Form of Subordinated Notes attached as Exhibit 4.2, and each is incorporated herein by reference as though it were fully set forth herein.

Item 9.01 Financial Statements and Exhibits

(d) Exhibits



The following exhibits are incorporated by reference into the Registration
Statement as exhibits thereto and are filed as part of this Current Report:
Exhibit             Description
4.1                   Second Supplemental Indenture between the Company and The Bank of New
                    York Mellon, dated May 26, 2022
4.2                   Form of Global Note for the Subordinated Notes (included in Exhibit
                    4.1)
5                     Opinion of Cleary Gottlieb Steen & Hamilton LLP
23                    Consent of Cleary Gottlieb Steen & Hamilton LLP (included in Exhibit 5)
104                 The cover page of this Current Report on Form 8-K, formatted as inline XBRL





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