CAMBRIDGE, Britain (AP) _ Astrazeneca PLC (AZN) on Friday reported fourth-quarter profit of $313 million.

The Cambridge, Britain-based company said it had net income of 12 cents per share. Earnings, adjusted for one-time gains and costs, came to 45 cents per share.

The results did not meet Wall Street expectations. The average estimate of four analysts surveyed by Zacks Investment Research was for earnings of 53 cents per share.

The pharmaceutical posted revenue of $6.66 billion in the period.

For the year, the company reported profit of $1.34 billion, or 51 cents per share. Revenue was reported as $24.38 billion.

Astrazeneca shares have dropped 1% since the beginning of the year. The stock has climbed 35% in the last 12 months.

This story was generated by Automated Insights (http://automatedinsights.com/ap) using data from Zacks Investment Research. Access a Zacks stock report on AZN at https://www.zacks.com/ap/AZN

Automated Insights, source Associated Press News